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API · /complexes-api

Complex Portal API

degraded 3,747 Subscribers

The Complex Portal as an API, powered by EMBL-EBI — a manually curated, encyclopaedic database of stable macromolecular complexes: assemblies of two or more proteins (and sometimes nucleic acids, ligands or small molecules) that work together as a single functional unit, such as ribosomes, proteasomes, RNA and DNA polymerases, the spliceosome, respiratory-chain complexes and thousands more across many species. Search the complexes by keyword and optionally by organism, getting each complex's Complex Portal accession (CPX-…), name, organism, description and whether it is computationally predicted; read a complex's full curated record including its recommended and systematic names, synonyms, species, biological function, the participating subunits each with its molecule identifier (for example a UniProt accession) and stoichiometry, any associated ligands and diseases, the evidence type and cross-references to UniProt, Gene Ontology, Reactome, Wikidata and more; and pull just the subunit composition of a complex. Ideal for structural and systems biology, pathway and network analysis, protein-function research and bioinformatics pipelines. Complex accessions look like CPX-6036. Data from EMBL-EBI Complex Portal (IMEx consortium, CC-BY). For protein–protein interaction networks see the STRING API, for protein sequences UniProt, for biological pathways Reactome and for families & domains InterPro.

#complex-portal #macromolecular-complexes #proteins #structural-biology #bioinformatics #life-sciences #ebi
api.oanor.com/complexes-api
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Machine-readable spec so AI agents can integrate this API.

/api/complexes-api/openapi.json
/api/complexes-api/llms.txt

Discovery: GET /api/index.json lists every API.

API health

degraded
Uptime
93.75%
Server probes · 24h
Avg latency
362 ms
Server probes · 24h
Subscribers
3,747
active
Total calls
12
last 7 days
status Full status page → · 32 probes/24h

Pricing

Pick a tier — billed monthly, cancel anytime.

Free

Free

  • 565 calls / month
  • 2 requests / second
  • Hard cap (429 above quota, no overage)
  • 565 calls/month
  • 2 req/sec
  • Search, complexes & subunits
  • No credit card
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Starter

€6.70 /month

  • 21,200 calls / month
  • 6 requests / second
  • Hard cap (429 above quota, no overage)
  • 21.2k calls/month
  • 6 req/sec
  • Full complex records
  • Email support
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Pro

€20.80 /month

  • 91,500 calls / month
  • 15 requests / second
  • Hard cap (429 above quota, no overage)
  • 91.5k calls/month
  • 15 req/sec
  • Systems-biology pipelines
  • Priority support
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Mega

€57.50 /month

  • 395,000 calls / month
  • 40 requests / second
  • Hard cap (429 above quota, no overage)
  • 395k calls/month
  • 40 req/sec
  • High-throughput proteomics
  • Dedicated SLA
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Related APIs

Other APIs with overlapping tags.

Gene Ontology API

Gene function as an API — powered by EMBL-EBI's QuickGO and the Gene Ontology (GO), the standard vocabulary that describes what gene products do across three aspects: molecular function, biological process and cellular component. Given a gene or protein (a UniProt accession), list every GO annotation made for it — the GO term, its aspect, the qualifier, the evidence code, the supporting reference (e.g. a PubMed id), the organism and who assigned it — optionally filtered by aspect or organism. Look up any GO term to get its definition, aspect, synonyms and number of child terms; and search the ontology by name to find the right GO terms. GO term names are resolved automatically on annotations. From TP53 to any protein in any species, it is the backbone of functional genomics — ideal for enrichment analysis, annotation pipelines, bioinformatics and research tools. A gene-function annotation resource (which genes have which functions, with evidence) — distinct from generic ontology-term lookup. Open data from EMBL-EBI QuickGO and the GO Consortium (CC BY 4.0).

api.oanor.com/quickgo-api

EMDB API

The Electron Microscopy Data Bank (EMDB) as an API, powered by EMBL-EBI — the public archive of three-dimensional electron-microscopy density maps of proteins, nucleic acids and large macromolecular complexes. EMDB is the electron-microscopy counterpart of the Protein Data Bank, holding maps solved by single-particle cryo-EM, electron tomography and electron crystallography, the technique behind the recent "resolution revolution" in structural biology. /v1/search?q=ribosome searches the archive and returns each matching entry's EMDB id (e.g. EMD-1010), title, electron-microscopy method and resolution in ångström. /v1/entry?id=EMD-1010 returns an entry's metadata — its title, the EM method (single particle, tomography, …), the aggregation state, the resolution, the biological sample studied, classification keywords, the deposition, map-release and last-update dates, and the depositing authors. EMDB ids look like EMD-1010, and you may pass just the number. Ideal for structural-biology and cryo-EM tools, structure-comparison and visualisation apps, and education. Data from EMBL-EBI EMDB (public domain). This is the archive of experimental electron-microscopy MAPS — distinct from atomic-coordinate structures (the PDB), predicted structures (AlphaFold) and protein-sequence databases (UniProt).

api.oanor.com/emdb-api

AlphaFold API

The AlphaFold Protein Structure Database as an API, powered by EMBL-EBI and Google DeepMind. AlphaFold predicts the three-dimensional structure of a protein from its amino-acid sequence with experimental-level accuracy, and the database now covers over 200 million proteins — nearly every sequence in UniProt. Look up the AlphaFold model for any protein by its UniProt accession and get its gene and protein description, organism and sequence length, model version and creation date, the global confidence metric, the full amino-acid sequence, and direct download links to the predicted structure as mmCIF, PDB and BinaryCIF together with the Predicted Aligned Error (PAE) plot image and data; and read a protein's structural coverage — the AlphaFold predicted model(s) and any linked structures with their provider, model category, method and the UniProt residue range covered. Ideal for structural biology, drug discovery and target assessment, protein engineering, molecular visualisation and teaching. Proteins are identified by UniProt accession (for example P00520 or P38398). Data from the AlphaFold DB (CC-BY 4.0). For experimentally-determined 3D structures see the PDB API, for protein sequences and functional annotation the UniProt API, and for families & domains InterPro.

api.oanor.com/alphafold-api

PDB API

The RCSB Protein Data Bank as an API — 3D macromolecular structures of proteins, nucleic acids and complexes, powered by the official RCSB PDB data and search services. Fetch a structure entry by its 4-character PDB id for its title, experimental method (X-ray, cryo-EM, NMR), resolution, keywords, deposit and release dates, authors, primary citation and entity & assembly counts; run full-text search across the whole archive returning matching PDB ids and the total hit count; read a polymer entity for its protein or nucleic-acid name, one-letter sequence, length, source organism, chains and linked UniProt ids; read a biological assembly for its oligomeric state, symmetry and chain & atom counts; list the ligands bound in a structure with their component ids and names; and look up any chemical component (ligand) by code for its formula, weight, SMILES and InChIKey. Ideal for structural-biology and drug-discovery tools, molecular viewers, bioinformatics pipelines, education apps and research dashboards.

api.oanor.com/pdb-api

Frequently asked questions

Quick answers about pricing, quotas, and integration.

How do I get an API key for Complex Portal API?
Sign up for free at oanor.com, generate an API key from the developer dashboard, and call Complex Portal API with the x-oanor-key header. No credit card needed for the free tier.
What's the rate limit for Complex Portal API?
Free tier allows 1 request per second. Paid plans scale up to 50 requests per second on the Mega tier. Hard limits return HTTP 429 above the quota — no surprise overage charges.
How much does Complex Portal API cost?
Complex Portal API has a free tier with 100 calls / month. Paid plans start at €6.70 / month with higher quotas and faster rate limits.
Can I cancel my subscription anytime?
Yes. Plans are billed monthly and you can cancel anytime from your billing dashboard. No long-term contracts and no cancellation fee.
Is Complex Portal API GDPR-compliant?
All requests to Complex Portal API go through our EU-based gateway. Your upstream API key never leaves our server and no personal data is shared with the upstream provider beyond the request you send.

Pick an endpoint from the list on the left to see its details and try it.

Code snippets

Sign up to get an API key, then call any path under your slug.

curl https://api.oanor.com/complexes-api/SOME_PATH \
  -H "x-oanor-key: oanor_test_..."
const res = await fetch("https://api.oanor.com/complexes-api/SOME_PATH", {
  headers: { "x-oanor-key": "oanor_test_..." }
});
const data = await res.json();
$ch = curl_init("https://api.oanor.com/complexes-api/SOME_PATH");
curl_setopt($ch, CURLOPT_RETURNTRANSFER, true);
curl_setopt($ch, CURLOPT_HTTPHEADER, ["x-oanor-key: oanor_test_..."]);
$response = curl_exec($ch);
import requests
r = requests.get(
    "https://api.oanor.com/complexes-api/SOME_PATH",
    headers={"x-oanor-key": "oanor_test_..."},
)
print(r.json())

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