#protein-structure

The AlphaFold Protein Structure Database as an API, powered by EMBL-EBI and Google DeepMind. AlphaFold predicts the three-dimensional structure of a protein from its amino-acid sequence with experimental-level accuracy, and the database now covers over 200 million proteins — nearly every sequence in UniProt. Look up the AlphaFold model for any protein by its UniProt accession and get its gene and protein description, organism and sequence length, model version and creation date, the global confidence metric, the full amino-acid sequence, and direct download links to the predicted structure as mmCIF, PDB and BinaryCIF together with the Predicted Aligned Error (PAE) plot image and data; and read a protein's structural coverage — the AlphaFold predicted model(s) and any linked structures with their provider, model category, method and the UniProt residue range covered. Ideal for structural biology, drug discovery and target assessment, protein engineering, molecular visualisation and teaching. Proteins are identified by UniProt accession (for example P00520 or P38398). Data from the AlphaFold DB (CC-BY 4.0). For experimentally-determined 3D structures see the PDB API, for protein sequences and functional annotation the UniProt API, and for families & domains InterPro.

api.oanor.com/alphafold-api

The RCSB Protein Data Bank as an API — 3D macromolecular structures of proteins, nucleic acids and complexes, powered by the official RCSB PDB data and search services. Fetch a structure entry by its 4-character PDB id for its title, experimental method (X-ray, cryo-EM, NMR), resolution, keywords, deposit and release dates, authors, primary citation and entity & assembly counts; run full-text search across the whole archive returning matching PDB ids and the total hit count; read a polymer entity for its protein or nucleic-acid name, one-letter sequence, length, source organism, chains and linked UniProt ids; read a biological assembly for its oligomeric state, symmetry and chain & atom counts; list the ligands bound in a structure with their component ids and names; and look up any chemical component (ligand) by code for its formula, weight, SMILES and InChIKey. Ideal for structural-biology and drug-discovery tools, molecular viewers, bioinformatics pipelines, education apps and research dashboards.

api.oanor.com/pdb-api