UniProt API
The UniProt protein knowledge base as an API, powered by the official UniProt REST service curated by EMBL-EBI, SIB and PIR. Look up any protein by its UniProt accession for protein and gene names, organism, length, mass, function, keywords, Gene Ontology (GO) terms and linked PDB 3D structures; run full-text protein searches filtered by organism (NCBI taxon id) and Swiss-Prot review status; fetch amino-acid sequences with FASTA, molecular weight and CRC64 checksum; list sequence features such as signal peptides, chains, domains, active and binding sites, modified residues and natural variants, with a by-type breakdown; resolve NCBI taxonomy nodes with their full lineage; and pull reference proteomes with protein counts and genome-assembly ids. Across all kingdoms of life, from human to bacteria. Ideal for bioinformatics pipelines, drug-discovery and proteomics tools, sequence-analysis dashboards, academic research apps and life-science chatbots.
api.oanor.com/uniprot-api