A gene's constraint & location

Code snippets

curl "https://api.oanor.com/gnomad-api/v1/gene" \
  -H "x-oanor-key: oanor_test_..."

await fetch("https://api.oanor.com/gnomad-api/v1/gene", {
  headers: { "x-oanor-key": "oanor_test_..." }
});

$ch = curl_init("https://api.oanor.com/gnomad-api/v1/gene");
curl_setopt($ch, CURLOPT_HTTPHEADER, ["x-oanor-key: oanor_test_..."]);
curl_setopt($ch, CURLOPT_RETURNTRANSFER, true);
$out = curl_exec($ch);

import requests
requests.get(
    "https://api.oanor.com/gnomad-api/v1/gene",
    headers={"x-oanor-key": "oanor_test_..."}
)

Example response

A real response from this endpoint, captured by the latest health check.

{
    "data": {
        "gene": {
            "name": "BRCA1 DNA repair associated",
            "stop": 43170245,
            "chrom": "17",
            "flags": [],
            "start": 43044295,
            "strand": "-",
            "symbol": "BRCA1",
            "gene_id": "ENSG00000012048",
            "constraint": {
                "pli": 5.517117679826164e-38,
                "loeuf": 0.927589724465447,
                "mis_z": 1.73357180717296,
                "syn_z": 2.040732980468744,
                "oe_lof": 0.8061824760986327,
                "oe_mis": 0.9127915412080277,
                "expected_lof": 173.65795480634046,
                "observed_lof": 140,
                "oe_lof_lower": 0.7028371223870614,
                "oe_lof_upper": 0.927589724465447
            },
            "canonical_transcript": "ENST00000357654"
        }
    },
    "meta": {
        "timestamp": "2026-06-01T08:13:53.981Z",
        "request_id": "015d71f6-ce78-40d4-8018-3ab420bcf99c"
    },
    "status": "ok",
    "message": "Gene retrieved",
    "success": true
}