Background: This study aims to comprehensively characterize the dynamic succession of the salivary microbiome and metabolic reprogramming in type 2 diabetes mellitus (T2DM) patients across progressive stages of periodontitis (Stage I–IV) using an integrated multi-omics approach. We specifica", "submission_date": "20260203" }, { "title": "Bilophila wadsworthia inhibits lifestyle intervention response in Gestational Diabetes Mellitus via L-glutamine regulation", "accession": "MTBLS13807", "organisms": [ "Homo sapiens" ], "study_type": null, "description": "
Fecal samples were collected from 26 pregnant women with gestational diabetes mellitus (GDM) prior to and following a lifestyle intervention study, and subsequently analyzed using untargeted metabolomics.
", "submission_date": "20260130" }, { …(truncated, see openapi.json for full schema) ``` #### `GET /v1/study` — A study's full metadata **Parameters:** - `id` (query, required, string) — MetaboLights accession, e.g. MTBLS1 Example: `MTBLS1` **Example:** ```bash curl -H "x-oanor-key: $KEY" \ "https://api.oanor.com/metabolights-api/v1/study?id=MTBLS1" ``` **Response:** ```json { "data": { "study": { "title": "A metabolomic study of urinary changes in type 2 diabetes in human compared to the control group", "assays": [ { "platform": "Nuclear Magnetic Resonance (NMR) - - - Bruker", "technology": "NMR spectroscopy assay", "measurement": "untargeted analysis" } ], "people": [ { "name": "Reza M Salek", "roles": [ "principal investigator role" ], "affiliation": "University of Cambridge" }, { "name": "Jules L Griffin", "roles": [ "principal investigator role" ], "affiliation": "University of Cambridge" } ], "status": "Public", "factors": [ "Gender", "Metabolic syndrome" ], "ftp_url": "http://ftp.ebi.ac.uk/pub/databases/metabolights/studies/public/MTBLS1", "license": "EMBL-EBI Terms of Use", "accession": "MTBLS1", "submitters": [ "r7salek@gmail.com", "jules.griffin@mrc-hnr.cam.ac.uk" ], "description": "Type 2 diabetes mellitus is the result of a combination of …(truncated, see openapi.json for full schema) ``` ### Workflow #### `GET /v1/organisms` — Organisms studied **Parameters:** - `id` (query, required, string) — MetaboLights accession Example: `MTBLS1` **Example:** ```bash curl -H "x-oanor-key: $KEY" \ "https://api.oanor.com/metabolights-api/v1/organisms?id=MTBLS1" ``` **Response:** ```json { "data": { "count": 1, "study": "MTBLS1", "organisms": [ { "organism": "Homo sapiens", "organism_part": "urine", "term_accession": "http://purl.obolibrary.org/obo/NCBITaxon_9606" } ] }, "meta": { "timestamp": "2026-06-01T08:13:27.705Z", "request_id": "dfb36041-51c7-4d0d-831b-993dbf92d753" }, "status": "ok", "message": "Organisms retrieved", "success": true } ``` #### `GET /v1/protocols` — The analytical workflow **Parameters:** - `id` (query, required, string) — MetaboLights accession Example: `MTBLS1` **Example:** ```bash curl -H "x-oanor-key: $KEY" \ "https://api.oanor.com/metabolights-api/v1/protocols?id=MTBLS1" ``` **Response:** ```json { "data": { "count": 7, "study": "MTBLS1", "protocols": [ { "name": "Sample collection", "type": "Sample collection", "parameters": [], "description": "For the human studies, midstream urine (~15 ml) samples were collected and frozen from each volunteer. In total, 84 samples were collected from 12 healthy volunteers (7 time points, 8 males and 4 females) and 50 samples from 30 T2DM patients (1-3 time points, 17 males and 13 females) with well-controlled blood glucose maintained at normal concentrations by diet, following the guidelines issued by the American Diabetes Association, rather than medication. T2DM patients agreed to stop treatment with oral anti-diabetic agents during the study. Subjects went through a washout period of 4 wk before sample collection and abstained from alcohol during the study; diet was controlled throughout the study." }, { "name": "Extraction", "type": "Extraction", "parameters": [ "Extraction Method" ], "description": "For the human studies, midstream urine (∼15 ml) samples were collected and frozen from each volunteer. In total, 84 samples were collected from 12 healthy volunteers (7 time points, 8 males and 4 females) and 50 samples from 30 T2DM patients (1–3 time points, 17 males and 13 females) with well-controlled …(truncated, see openapi.json for full schema) ``` ### Meta #### `GET /v1/meta` — Usage notes **Example:** ```bash curl -H "x-oanor-key: $KEY" \ "https://api.oanor.com/metabolights-api/v1/meta" ``` **Response:** ```json { "data": { "note": "Open metabolomics studies archive. MetaboLights is the world's premier repository for metabolomics experiments (NMR & mass-spectrometry), a sister resource to PRIDE (proteomics). /v1/search?query=diabetes = search public studies (accession, title, description, organism, study type); /v1/study?id=MTBLS1 = a study's full metadata (title, abstract, status, submission & release dates, study-design descriptors, experimental factors, analytical assays with measurement & technology type and platform, contributors and roles, linked publications with DOI/PubMed, submitters, sample count, FTP download URL, data license); /v1/protocols?id=MTBLS1 = the analytical workflow — each protocol's name, type, description and parameters (sample collection, extraction, chromatography, NMR/MS spectroscopy, data transformation, metabolite identification); /v1/organisms?id=MTBLS1 = the organisms and organism parts studied with their ontology term. Study accessions look like MTBLS1. Data from EMBL-EBI MetaboLights. For proteomics datasets see the PRIDE API, for protein sequences UniProt, for biomedical literature Europe PMC.", "source": "EMBL-EBI MetaboLights REST API (ebi.ac.uk/metabolights)", "endpoints": [ "/v1/search", "/v1/study", "/v1/protocols", "/v1/organisms", "/v1/meta" ] }, "meta": { "timestamp": "2026-06-01T08:13:28.008Z", "request_id": "9b406c8c-91 …(truncated, see openapi.json for full schema) ``` --- Marketplace page: https://www.oanor.com/api/metabolights-api OpenAPI spec: https://www.oanor.com/api/metabolights-api/openapi.json